Epithalon

Yes. Epithalon, Epitalon and Epithalone are spellings of the same synthetic tetrapeptide, Ala-Glu-Asp-Gly. It was developed by Vladimir Khavinson's group at the St. Petersburg Institute of Bioregulation and Gerontology, based on a peptide extract of the pineal gland called epithalamin.

Epitalon (Epithalon) is a synthetic tetrapeptide, Ala-Glu-Asp-Gly, studied mainly in Russian aging research. NAD+ is a dinucleotide coenzyme present in every cell, not a peptide. Both appear in aging research, but they are chemically unrelated and act on different pathways.

No. Epitalon (also spelled Epithalon) is a synthetic tetrapeptide, Ala-Glu-Asp-Gly, developed in Russia by Vladimir Khavinson's group and based on a pineal gland extract; it is studied in aging research. Ipamorelin is a pentapeptide that acts on the ghrelin receptor. Neither is a growth hormone, which is a 191-amino-acid protein, and they are unrelated to each other.

They come from research on different glands. Thymosin alpha-1 is a 28-amino-acid peptide first isolated from thymus tissue and studied in immunology. Epitalon (Epithalon) is a synthetic tetrapeptide, Ala-Glu-Asp-Gly, developed in Russia from research on a pineal-gland extract and studied in aging research. They differ in size, origin and research area.

They are different peptides. Epithalon is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) developed in Russia from research on a pineal-gland extract and studied in aging research. Glutathione is a naturally occurring tripeptide with an unusual gamma peptide bond and a free thiol group, studied in redox biochemistry. Epithalon contains no cysteine and has no thiol group.

They are unrelated peptides. DSIP is a nonapeptide (Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu) isolated in 1977 from rabbit blood by Swiss researchers and named for sleep research. Epithalon is a much smaller synthetic tetrapeptide (Ala-Glu-Asp-Gly) developed in Russia from work on pineal-gland extracts, and it is studied mainly in aging and telomerase research. They share no sequence, origin or known target.

Epithalon (also spelled Epitalon; sometimes called AEDG peptide) is a synthetic tetrapeptide, Ala-Glu-Asp-Gly, with a molecular weight of about 390 Da. It was developed by Vladimir Khavinson's group in St. Petersburg as a synthetic counterpart of epithalamin, a peptide extract of the pineal gland. The figure on the label, such as 10 mg, is the amount of peptide in the vial.

Published research on Epithalon has been mainly preclinical, in cell culture, rodent and fruit-fly models, examining telomerase activity and telomere length, gene expression, pineal-gland and melatonin signaling, and lifespan in aging models. A small number of clinical studies have been published, largely by the same Russian research group. Findings in cells or animals do not establish effects in people.

No. Epitalon has not been approved by the FDA, and no U.S. clinical-trial or New Drug Application program for it is on record. As of October 2026 it is an unapproved research peptide in the United States, and the material sold here is a laboratory reagent only.

"Peptide bioregulator" is a term used by Vladimir Khavinson's group for the short peptides it derived from or modeled on organ extracts, and Epitalon is the best known of them, modeled on a pineal-gland extract. The term describes that group's research concept; it is not a recognized pharmacological class used by regulators.

Both are short synthetic peptides from Vladimir Khavinson's research group. Epithalon is a tetrapeptide, Ala-Glu-Asp-Gly, modeled on a pineal-gland extract. Pinealon is a tripeptide, Glu-Asp-Arg, studied mainly in neuroscience research. They have different sequences and lengths and are separate compounds; only Epithalon is sold here.

No. Epitalon is a tetrapeptide made of natural L-amino acids, Ala-Glu-Asp-Gly. SS-31 (elamipretide) is a different, synthetic tetrapeptide, D-Arg-Dmt-Lys-Phe-NH2, containing a D-amino acid and a modified tyrosine (2',6'-dimethyltyrosine); it was designed to concentrate in the inner mitochondrial membrane, where it binds the lipid cardiolipin. They share only their length.

NA Epithalon is a name some suppliers use for a chemically modified form of the peptide, usually described as N-acetyl Epitalon amidate: the same Ala-Glu-Asp-Gly sequence with an acetyl group on the N-terminus and an amide on the C-terminus, end-caps commonly added to slow enzymatic breakdown. The Epithalon sold here is the unmodified tetrapeptide.

Epithalon: molecular formula C14H22N4O9; molecular weight 390.35 g/mol; CAS number 307297-39-8. Sequence: Ala-Glu-Asp-Gly (AEDG). Match these identifiers against the Certificate of Analysis for the lot.

Yes. Each lot has its own Certificate of Analysis, linked on this page for the current lot of each size: 50mg (99.54% HPLC purity); 100mg (99.24% HPLC purity). Past certificates are archived in the COA library; contact us with the lot number on the vial label if a certificate is missing.

99.24% (HPLC, current lot). Purity is measured by high-performance liquid chromatography (HPLC) and reported on the lot's Certificate of Analysis.

Epithalon is supplied as lyophilized powder in a sealed vial in 2 sizes: 50mg, 100mg. In stock and dispatched in 1–2 business days. Quantity pricing applies automatically at 5+ and 10+ vials of the same size.

Store sealed at −20 °C, dry and protected from light.