How USA Prime Peptides tests and documents every product
Every lot we sell is tested by an independent laboratory for purity (HPLC), identity (mass spectrometry) and endotoxins (LAL), and the results are published as a lot-specific Certificate of Analysis (COA) that anyone can read before buying. This page explains that process, how to check the vial you receive, what a COA can and cannot tell you, and how we source the scientific information on product pages.
Our documentation standard at a glance
- One certificate per lot, not per product: a COA only describes the batch it tested.
- Purity by HPLC: our specification is ≥99% unless a product states a different grade in its name (for example, a 95% grade).
- Identity by mass spectrometry: the observed molecular weight is compared with the theoretical value listed in each product's specifications.
- Endotoxin by LAL, with heavy-metals results where listed.
- Public records: 55 current-lot certificates across 48 catalog products, plus the full archive in the COA library.
- Traceable labels: lot number and a QR code linking to the certificate on every vial.
From synthesis to shipment
- 1
Synthesis
Peptides are made by solid-phase peptide synthesis at our partner laboratory, purified, and freeze-dried (lyophilized) into a stable powder. How solid-phase synthesis works.
- 2
Lot assignment
Each production batch receives a lot number when we receive it. The lot number is printed on every vial label and ties the vial to its test results, receiving date and stock records.
- 3
Independent testing
A sample of the finished lot is tested by an independent third-party laboratory: HPLC for purity, mass spectrometry to confirm identity (observed vs. theoretical molecular weight), and LAL for bacterial endotoxins. Heavy-metals results are reported where listed on the certificate.
- 4
Publication
The Certificate of Analysis for the current lot is linked on the product page and archived in the public COA library. Vial labels carry a QR code that opens the matching certificate.
- 5
Storage and shipping
Temperature-sensitive items ship with cold packs. Storage guidance for each compound is on its product page and in our lyophilized peptide storage guide.
How to check the vial you received
- Find the lot number on the vial label, or scan its QR code.
- Open that lot's certificate from the product page or the COA library. The compound name, strength and lot number must all match the label.
- Compare the observed mass on the certificate with the molecular weight in the product's specifications to confirm identity.
- Read the HPLC purity and endotoxin results. Our guide to reading a Certificate of Analysis explains each section.
- If anything does not match, contact [email protected] within 7 days with photos and the lot number. A COA mismatch qualifies for replacement or refund under our Refund Policy.
What a Certificate of Analysis does and does not tell you
It does tell you what the laboratory measured in a sample of one lot: its purity by HPLC, whether its molecular weight matches the labeled compound, and its endotoxin level.
It does not describe other lots, certify sterility unless sterility testing is listed, or establish that a compound is safe or effective for any use. HPLC purity is relative to what the detector can see, which is why it is paired with mass-spectrometry identity (see HPLC purity explained and LAL endotoxin testing).
Test results are a research-verification record, not a release for human, veterinary, diagnostic or therapeutic use.
How we source scientific information
Each product page has a research profile: what the compound is, its proposed mechanism, its chemical identifiers, its FDA development stage, and a list of cited studies from the peer-reviewed literature, linked to PubMed or the publisher wherever possible. The full set is browsable in the research library.
Every cited study is labelled by design: human study, preclinical: animal, preclinical: cell / in-vitro, or review. Chemistry, analytical-method and background papers are left unlabelled. Each compound also carries an overall evidence level:
- Established (for the approved drug)
- The molecule is the active ingredient of an FDA-approved drug, so controlled human data exist for that regulated product. Those findings do not transfer to research-grade material.
- Emerging (human trials, investigational)
- Phase 2 or 3 human trials have been run or are underway, but the molecule is not approved. Results are investigational.
- Early human data
- Only Phase 1 studies, which mainly assess tolerability and pharmacokinetics, have been reported.
- Limited human evidence
- No FDA development program; a small number of human reports exist, but the evidence is predominantly preclinical.
- Preclinical / insufficient human evidence
- The literature is cell (in-vitro) and animal work. Findings cannot be generalized to humans.
We summarize published research for scientific context only. We do not provide dosing, administration or protocol guidance, and nothing on this site is a claim that a product treats, cures or prevents any condition. See FDA development stages explained.
Testing material you already own
Our independent lab testing service forwards peptides you already hold, from any source, to an independent US laboratory and issues a certificate with a public verification code. Anyone can check that code on the certificate verification page.