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5-amino-1mq
5-Amino-1-methylquinolinium; small-molecule quinolinium compound (not a peptide).
5-amino-1mq FAQ
What is 5-Amino-1MQ?
5-Amino-1MQ (5-amino-1-methylquinolinium) is a small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme in the NAD+ salvage and methylation pathways. It is studied in metabolism research. Despite being sold alongside peptides, it is not a peptide.
Is 5-Amino-1MQ a peptide?
No. 5-Amino-1MQ is a small organic molecule built on a quinoline ring, with no amino-acid chain. It is often sold by peptide suppliers because it is used in the same areas of metabolism research.
Why is 5-Amino-1MQ orange or red?
Quinolinium compounds like 5-Amino-1MQ are naturally colored. The shade, from yellow to orange or reddish, depends on the salt form, the crystal form and how finely divided the powder is. Color alone is not a purity test; identity and purity are confirmed by the lot's Certificate of Analysis.
5-Amino-1MQ vs. MOTS-c vs. NAD+
These are three different kinds of molecule that appear together in metabolism research. 5-Amino-1MQ is a small-molecule inhibitor of the enzyme nicotinamide N-methyltransferase (NNMT). MOTS-c is a 16-amino-acid peptide encoded in mitochondrial DNA. NAD+ (nicotinamide adenine dinucleotide) is a coenzyme found in every living cell. Only MOTS-c is a peptide.
What has 5-Amino-1MQ been studied for in research?
Published research on 5-Amino-1MQ has been preclinical, mainly in cultured adipocytes and mouse models, examining the enzyme nicotinamide N-methyltransferase (NNMT) and its links to NAD+ salvage, methylation (SAM) metabolism and cellular energy metabolism. It was developed by researchers at the University of Texas Medical Branch as a membrane-permeable NNMT inhibitor. Findings in cells or animals do not establish effects in people.
Is 5-Amino-1MQ FDA approved?
No. 5-Amino-1MQ has not been approved by the FDA for any use, and it is not an approved medicine in any country. Published work on it has been preclinical. It is sold here strictly as a research compound for laboratory use, not for human or veterinary use.
How should 5-Amino-1MQ be stored?
Keep sealed 5-Amino-1MQ powder cool, dry and protected from light; refrigeration at 2–8 °C, or −20 °C for long-term storage, is a sensible default for research compounds. Let the container reach room temperature before opening so moisture does not condense on the powder. Once in solution, keep it refrigerated and follow the storage guidance on the label and Certificate of Analysis.
Is 5-Amino-1MQ legal?
5-Amino-1MQ is not a controlled substance under US federal law, and it can be purchased as a research chemical for laboratory use. It is not an approved drug, so it may not be sold for human consumption or marketed with health claims. This is general information, not legal advice.
AICAR vs. 5-Amino-1MQ
Both are small molecules (neither is a peptide) used in metabolism research, but they act at different points. AICAR is a nucleoside that cells convert to ZMP, an AMP mimic that activates AMP-activated protein kinase (AMPK). 5-Amino-1MQ is a quinolinium compound that inhibits the enzyme nicotinamide N-methyltransferase (NNMT), which sits in the NAD+ salvage and methylation pathways.
5-Amino-1MQ vs. SLU-PP-332
They are different small molecules with different targets. 5-Amino-1MQ inhibits the enzyme nicotinamide N-methyltransferase (NNMT). SLU-PP-332 is a synthetic agonist of the estrogen-related receptors (ERRα, β and γ), nuclear receptors involved in mitochondrial gene programs, developed at Saint Louis University. Neither is a peptide, and neither is FDA approved. MOTS-c, by contrast, is a peptide, and AICAR acts through AMPK.
5-Amino-1MQ vs. retatrutide
They are different classes of molecule. 5-Amino-1MQ is a small quinolinium compound that inhibits the enzyme NNMT inside cells. Retatrutide is a 39-amino-acid, fatty-acid-modified peptide that activates three cell-surface receptors (GIP, GLP-1 and glucagon). 5-Amino-1MQ is not a GLP-1 agonist and does not act on incretin receptors.
What are the identifiers for 5-amino-1mq?
5-amino-1mq: molecular formula C10H11N2+ (commonly supplied as the iodide salt, C10H11IN2); molecular weight 159.21 g/mol (cation); approximately 286.11 g/mol as the iodide salt. Match these identifiers against the Certificate of Analysis for the lot.
Does 5-amino-1mq come with a Certificate of Analysis?
Yes. Each lot has its own Certificate of Analysis, linked on this page for the current lot of each size: 50mg (99.36% HPLC purity). Past certificates are archived in the COA library; contact us with the lot number on the vial label if a certificate is missing.
What purity is 5-amino-1mq?
99.36% (HPLC, current lot). Purity is measured by high-performance liquid chromatography (HPLC) and reported on the lot's Certificate of Analysis.
What sizes of 5-amino-1mq are available?
5-amino-1mq is supplied as lyophilized powder in a sealed vial: 50mg. In stock and dispatched in 1–2 business days. Quantity pricing applies automatically at 5+ and 10+ vials of the same size.
How should 5-amino-1mq be stored?
Store sealed at −20 °C, dry and protected from light.
More on testing, storage and handling in the full FAQ.
